Kate Collins

Ithaca

Contributor at Freelance

✨writer✨artist✨former photojournalist✨speculative fiction novel in progress✨

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Articles

My colleagues are all women. A female work environment has a lot of perks, but there's one thing I really don't like.

2 weeks ago | businessinsider.com | Lauryn Haas |Kate Collins |Henry Blodget

When I walked into work last year on my birthday, there was an envelope with my name written in cursive on my desk. I was less than three months into a new job and hadn't announced my birthday. Being an introvert, a slight discomfort rose as I opened the envelope. The discomfort dissipated as I read the personalized messages written by my colleagues. I was grateful for the simple gesture; this was the first time I received a birthday card at work.
The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy

Aug 2, 2024 | biorxiv.org | Kate Collins |Srinivas Kamath |Tahlia R. Meola |Anthony Wignall

AbstractAtypical antipsychotics are crucial for the management of schizophrenia and bipolar disorder, yet they exhibit significant pharmacokinetic variability which leads to inconsistent therapeutic responses. This study investigates the hypothesis that gut microbiome composition critically influences the oral bioavailability of lurasidone, a poorly soluble weak base antipsychotic with pH-dependent solubility.
The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy

Aug 2, 2024 | biorxiv.org | Kate Collins |Srinivas Kamath |Tahlia R. Meola |Anthony Wignall

AbstractAtypical antipsychotics are crucial for the management of schizophrenia and bipolar disorder, yet they exhibit significant pharmacokinetic variability which leads to inconsistent therapeutic responses. This study investigates the hypothesis that gut microbiome composition critically influences the oral bioavailability of lurasidone, a poorly soluble weak base antipsychotic with pH-dependent solubility.
The atypical antipsychotics lurasidone and olanzapine exert contrasting effects on the gut microbiome and metabolic function of rats

Jul 29, 2024 | bpspubs.onlinelibrary.wiley.com | Srinivas Kamath |UniSa Clinical |Alexander Hunter |Kate Collins

CD68 cluster of differentiation 68 ChREBP carbohydrate regulatory element binding protein F:B Firmicutes:Bacteroidetes LOQ limit of quantification OTU operational taxonomical unit PCoA principal coordinate analysis PUL polysaccharide utilisation loci SCFA short chain fatty acid SREBP-1c sterol-regulatory element binding protein 1c What is already known? Olanzapine induces weight gain by disrupting the gut microbiome.
Prebiotic Supplementation Modulates the Gut Microbiome for Improving Oral Antipsychotic Bioavailability

Jul 19, 2024 | biorxiv.org | Kate Collins |Srinivas Kamath |Tahlia R. Meola |Anthony Wignall

AbstractThis study investigates the impact of gut microbiome composition on the bioavailability and biodistribution of lurasidone hydrochloride, an atypical antipsychotic used in treating mental health conditions. The research aims to uncover the relationship between gut metabolome, specifically short-chain fatty acids (SCFAs), and lurasidone absorption through modulation of intestinal pH.
I shopped at Trader Joe's daily until Aldi won me over. I finally understand why people love the chain so much.

Apr 24, 2024 | yahoo.com | Kate Collins

I used to shop at Trader Joe's daily because it was close to work. However, after changing jobs, I began shopping at Aldi to save some money. I've grown to love Aldi's wide aisles, low prices, and great products. Before I shopped at Trader Joe's, I was never loyal to any one grocery store. Like many shoppers, my store choice was driven primarily by convenience: whichever grocer was closest to me became my go-to. That's why when I worked near Trader Joe's, I stopped there daily.
The atypical antipsychotic lurasidone positively modulates the gut microbiota in rats: A comparative study to olanzapine

Mar 3, 2024 | biorxiv.org | Srinivas Kamath |Alexander Hunter |Kate Collins |Anthony Wignall

AbstractAntipsychotics like olanzapine are associated with significant metabolic dysfunction, attributable to gut microbiota dysbiosis. A recent notion that most psychotropics are detrimental to the gut microbiota has arisen from consistent findings of metabolic adverse effects. However, unlike olanzapine, the metabolic effects of lurasidone are conflicting, with most reports observing weight loss rather than gain.
Constructing a Century

Jan 31, 2024 | blogs.library.duke.edu | Kate Collins

Post contributed by Shaina Leverett, Harry H. Harkins Intern for the Duke Centennial, Duke University ArchivesIf someone approached you and asked- “What is this thing you call Duke University? What does it mean? Where does it come from? Who makes it? Who continually makes it?” How would you respond to that? Four undergraduates applied to create an exhibit showcasing the last 100 years of Duke history.
Correction: The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells

Jan 2, 2024 | journals.plos.org | Bryan Burton |Kate Collins |Jordan Brooks |Karly Marx |Matthew Pawlus

There are errors in the Funding section. The correct Funding statement is: Research reported in this publication was supported by the South Dakota Biomedical Research Infrastructure Network (SD BRIN) through an Institutional Development Award (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant number P20GM103443.
Smooth Sailing: Mastering the Bureaucracy of Life at Sea » Explorersweb

Jan 1, 2024 | explorersweb.com | Kate Collins |Sam Anderson |Kris Annapurna |Jerry Kobalenko

The ability to sail off into the sunset, anchor in secluded bays, and access remote islands is the dream of many. But can you actually explore the world as you please? Well, sort of. Very basically, the United Nations Convention on The Law of the Sea provides for absolute freedom of navigation on the seas outside territorial waters. It also allows for “innocent passage” through territorial waters and Exclusive Economic Zones.

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Kate Catalano Collins @kcollins213

18 Nov 24

RT @JoelleTamraz: How amazing this writing life where we get to experiment with words, rewrite, change meanings, and some day, perhaps, con…

Kate Catalano Collins @kcollins213

13 Nov 24

RT @JoelleTamraz: You’ve written another book, so you think this first draft will flow in coherent order. Not so. First drafts are like swi…

Kate Catalano Collins @kcollins213

13 Sep 24

RT @harris_wins: BREAKING: Kamala Harris has filled a stadium in Wilkes-Barre, Pennsylvania to the brim. This is a county that voted for Tr…

Kate Collins

Articles

My colleagues are all women. A female work environment has a lot of perks, but there's one thing I really don't like.

The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy

The Oral Bioavailability of Lurasidone is Impacted by Changes to the Gut Microbiome: Implications for Antipsychotic Therapy

The atypical antipsychotics lurasidone and olanzapine exert contrasting effects on the gut microbiome and metabolic function of rats

Prebiotic Supplementation Modulates the Gut Microbiome for Improving Oral Antipsychotic Bioavailability

I shopped at Trader Joe's daily until Aldi won me over. I finally understand why people love the chain so much.

The atypical antipsychotic lurasidone positively modulates the gut microbiota in rats: A comparative study to olanzapine

Constructing a Century

Correction: The biotoxin BMAA promotes dysfunction via distinct mechanisms in neuroblastoma and glioblastoma cells

Smooth Sailing: Mastering the Bureaucracy of Life at Sea » Explorersweb

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