Kateryna D. Makova

Feb 22, 2024 | biorxiv.org | Kateryna D. Makova |Brandon Pickett |Robert Harris |Gabrielle Hartley

AbstractApes possess two sex chromosomes—the male-specific Y and the X shared by males and females. The Y chromosome is crucial for male reproduction, with deletions linked to infertility1. The X chromosome carries genes vital for reproduction and cognition2. Variation in mating patterns and brain function among great apes suggests corresponding differences in their sex chromosomes.

Dec 1, 2023 | biorxiv.org | Kateryna D. Makova |Brandon Pickett |Robert Harris |Gabrielle Hartley

IntroductionTherian X and Y chromosomes are thought to have originated from a pair of autosomes approximately 170 million years ago (MYA)1. The X chromosome, typically present in two copies in females and one copy in males, has mostly retained the gene content and order from the original autosomal pair2.