Kathy Vuksanaj

1 week ago | insideprecisionmedicine.com | Sophia Ktori |Kathy Vuksanaj

A common antidepressant may help boost the immune system’s ability to fight cancer, according to new research from UCLA. The study found that selective serotonin reuptake inhibitors (SSRIs) significantly improved T cell responses and reduced tumor growth in various cancer types, using both human and mouse models. Researchers also identified the serotonin transporter (SERT) as a potential new immune checkpoint target.

2 weeks ago | insideprecisionmedicine.com | Sophia Ktori |Kathy Vuksanaj

Measuring a cell’s density can reveal important clues about its state, as changes in water content and molecular composition during proliferation, differentiation, or cell death often affect density. However, tracking these subtle shifts at large scale and single-cell resolution has been challenging—until now. Researchers at the Massachusetts Institute of Technology (MIT) have developed a method to rapidly and accurately measure cell density, analyzing up to 30,000 cells per hour.

3 weeks ago | genengnews.com | Caroline Seydel |Kathy Vuksanaj

Home Topics Drug Discovery Crossing the Cell Membrane Without Viruses Because their gene editing platform is entirely based on RNA, Tessera Therapeutics can use lipid nanoparticles (LNPs) for delivery to the cells of interest. LNPs are less immunogenic and less expensive to manufacure than viruses. Because their gene editing platform is entirely based on RNA, Tessera Therapeutics can use lipid nanoparticles (LNPs) for delivery to the cells of interest.

1 month ago | insideprecisionmedicine.com | Sophia Ktori |Kathy Vuksanaj

A study led by NYU Langone Health and its Perlmutter Cancer Center scientists found that monitoring DNA fragments shed by dying tumor cells in the blood may accurately predict skin cancer recurrence. In the Phase III COMBI-AD clinical trial, researchers observed that about 80% of stage III melanoma patients with detectable circulating tumor DNA (ctDNA) prior to treatment eventually experienced a recurrence.

2 months ago | insideprecisionmedicine.com | Larissa Warneck-Silvestrin |Kathy Vuksanaj

With the advent of next-generation sequencing (NGS) technologies just over a decade ago, genomic information became available not only in labs, but also in clinical practice. Today, genomic testing is starting to play an important role in cancer patient care. Knowing the genetic makeup of a tumor can help oncologists determine the best therapeutic options for a patient, making genomic testing a growing part of precision medicine.