Kati Kristiansson

Oct 4, 2024 | ascpt.onlinelibrary.wiley.com | Kati Kristiansson |Kaisa Litonius |Noora Kulla |Petra Falkenbach

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Majority of people carry at least one actionable pharmacogenetic genotype, and the value of pharmacogenetic testing is widely accepted. However, only few studies have assessed the utility and cost-effects of pre-emptive pharmacogenetic testing in a scenario where all patients admitted to hospital would be genotyped. WHAT QUESTION DID THIS STUDY ADDRESS?

Mar 6, 2024 | nature.com | Minna K. Karjalainen |Eeva Sliz |Elias Allara |Weihua Zhang |Pekka Jousilahti |Kati Kristiansson | +46 more

AbstractGenome-wide association analyses using high-throughput metabolomics platforms have led to novel insights into the biology of human metabolism1,2,3,4,5,6,7. This detailed knowledge of the genetic determinants of systemic metabolism has been pivotal for uncovering how genetic pathways influence biological mechanisms and complex diseases8,9,10,11.

Feb 26, 2024 | nature.com | Martin Broberg |Teemu Palviainen |Samuel Jones |Katja Valli |Samuli Ripatti |Elisabeth Widén | +2 more

AbstractNightmares are vivid, extended, and emotionally negative or negative dreams that awaken the dreamer. While sporadic nightmares and bad dreams are common and generally harmless, frequent nightmares often reflect underlying pathologies of emotional regulation. Indeed, insomnia, depression, anxiety, or alcohol use have been associated with nightmares in epidemiological and clinical studies. However, the connection between nightmares and their comorbidities are poorly understood.