Kun Ping Lu

Dec 23, 2024 | pubs.rsc.org | Kun Ping Lu

Elucidating the Effect of Bromine Substitution in Asymmetric Quinoxaline Central Cores-Based Non-fullerene Acceptors on Molecular Stacking and Photovoltaic Performances The substitution optimization is an efficient method to construct non-fullerene acceptors (NFAs), and the electronegative fluorine and chlorine have been generally used. For the larger atom bromine, however, scarce researches touched it.

Jun 27, 2024 | biorxiv.org | YIFEI YANG |Yun-Chung Hsiao |Kun Ping Lu

AbstractGut microbiome is a group of microorganisms that plays important roles in contributing to health and diseases. These bacterial compositions have been demonstrated to impact bile acids (BAs) profiles, either by directly metabolizing primary BAs to secondary BAs or indirect ways through host metabolism by influencing BAs synthesis, transportation and conjugation in liver.

Jun 18, 2024 | science.org | Shane Wright |Kun Ping Lu |Wei Wong |Xiao Zhou

AbstractProtein phosphorylation is one of the most common mechanisms regulating cellular signaling pathways, and many kinases and phosphatases are proven drug targets. Upon phosphorylation, protein functions can be further regulated by the distinct isomerase Pin1 through cis-trans isomerization. Numerous protein targets and many important roles have now been elucidated for Pin1. However, no tools are available to detect or target cis and trans conformation events in cells.

Jun 18, 2024 | science.org | Shane Wright |Kun Ping Lu |Wei Wong

AbstractSuppression of GLP-1 release by a gut microbiota–derived metabolite induces polycystic ovary syndrome. SIGN UP FOR THE SCIENCEADVISER NEWSLETTER The latest news, commentary, and research, free to your inbox daily Polycystic ovary syndrome (PCOS) is an endocrine disorder that is characterized by hormonal imbalances, including hyperandrogenism, and that results in infertility and cardiovascular and metabolic abnormalities in women.

May 9, 2023 | futuremedicine.com | Kun Ping Lu |Rui Chen |Hua Yang |Yong Wang

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending or royalties. No writing assistance was utilized in the production of this manuscript.