Kylie S. Leung

Oct 11, 2024 | nature.com | Shiwei Wang |Ryan McMillan |Peng Yin |Laura Kiessling |Kylie S. Leung

AbstractExpansion microscopy (ExM) is in increasingly widespread use throughout biology because its isotropic physical magnification enables nanoimaging on conventional microscopes. To date, ExM methods either expand specimens to a limited range (~4–10× linearly) or achieve larger expansion factors through iterating the expansion process a second time (~15–20× linearly).