Laura Kiessling

Oct 11, 2024 | nature.com | Shiwei Wang |Ryan McMillan |Peng Yin |Laura Kiessling |Kylie S. Leung

AbstractExpansion microscopy (ExM) is in increasingly widespread use throughout biology because its isotropic physical magnification enables nanoimaging on conventional microscopes. To date, ExM methods either expand specimens to a limited range (~4–10× linearly) or achieve larger expansion factors through iterating the expansion process a second time (~15–20× linearly).

Apr 19, 2023 | nature.com | Jennifer Ross |Victoria Marando |Alan Cartmell |Bernard Henrissat |José Munoz-Munoz |Laura Kiessling | +5 more

AbstractBacterial cell growth and division require the coordinated action of enzymes that synthesize and degrade cell wall polymers. Here, we identify enzymes that cleave the d-arabinan core of arabinogalactan, an unusual component of the cell wall of Mycobacterium tuberculosis and other mycobacteria.