
Lisa Gartner
Deputy Editor, Long-Term Investigations at The Washington Post
Editor @washingtonpost’s long-term investigations team. Formerly @sfchronicle @tb_times @phillyinquirer. She/her
Articles
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Oct 22, 2024 |
nature.com | Maria Kiourlappou |Lisa Gartner |Nicholas E. Ilott |Fadi Issa |Joanna Hester |Jason Turner | +12 more
AbstractPrecision medicine in immune-mediated inflammatory diseases (IMIDs) requires a cellular understanding of treatment response. We describe a therapeutic atlas for Crohn’s disease (CD) and ulcerative colitis (UC) following adalimumab, an anti-tumour necrosis factor (anti-TNF) treatment. We generated ~1 million single-cell transcriptomes, organised into 109 cell states, from 216 gut biopsies (41 subjects), revealing disease-specific differences.
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