Maria Koromina

1 month ago | nature.com | Pravesh Parekh |Sara Stinson |Maria Koromina |Jaroslav Rokicki |Ida E Sønderby |Nadine Staples Parker | +11 more

AbstractMetabolites in plasma form biosignatures of a range of common complex human diseases. Discovering variants with pleiotropic effects across metabolites can reveal underlying biological mechanisms. We therefore performed uni- and multivariate genome-wide association studies (GWAS) on 249 circulating metabolic markers across 328,006 UK Biobank and Estonian Biobank participants.