
Mark Anderson
Articles
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Aug 21, 2024 |
nature.com | Mark Anderson
The AIRE protein drives the expression of tissue-restricted self-antigens, required to induce immune tolerance for self-proteins. New work shows the importance of an external interaction between AIRE and the transcriptional activator CBP/p300, and an internal competition for nuclear-condensate formation.
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Jun 19, 2024 |
nature.com | Michael A. Skinnider |Matthieu Gautier |Claudia Kathe |Thomas Hutson |Achilleas Laskaratos |Viviana Aureli | +7 more
AbstractHere, we introduce the Tabulae Paralytica—a compilation of four atlases of spinal cord injury (SCI) comprising a single-nucleus transcriptome atlas of half a million cells, a multiome atlas pairing transcriptomic and epigenomic measurements within the same nuclei, and two spatial transcriptomic atlases of the injured spinal cord spanning four spatial and temporal dimensions.
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Jun 2, 2024 |
mdpi.com | Francesco Rizzetto |Michael Blake |Mark Anderson |Luigi Asmundo
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Apr 25, 2024 |
mdpi.com | Eva Duvalyan |Sam Brondfield |Robert J. Rushakoff |Mark Anderson
All articles published by MDPI are made immediately available worldwide under an open access license. No specialpermission is required to reuse all or part of the article published by MDPI, including figures and tables. Forarticles published under an open access Creative Common CC BY license, any part of the article may be reused withoutpermission provided that the original article is clearly cited. For more information, please refer tohttps://www.mdpi.com/openaccess.
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Apr 24, 2024 |
nature.com | Eduardo Martinez |Eduardo Martínez |Rashi Ranjan |Mark Anderson
AbstractCD4+ T cells recognize peptide antigens presented on class II major histocompatibility complex (MHC-II) molecules to carry out their function. The remarkable diversity of T cell receptor sequences and lack of antigen discovery approaches for MHC-II make profiling the specificities of CD4+ T cells challenging.
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