Mark Christian

1 month ago | tandfonline.com | Mark Christian |Zhenyu Wang |Qiyu Xu |Lijuan Hou

AbstractPolysaccharides represent a crucial and extensively utilized bioactive fraction in natural products, which are employed in the treatment of metabolic disorders due to their significant therapeutic potential. Recently, food-derived polysaccharides (FPs) have emerged as significant substances in obesity management, valued for their ability to activate thermogenic fat. This review discusses the correlation between the structural features of FPs and their efficacy in combating obesity.

Feb 19, 2025 | endocrine-abstracts.org | Mark Christian |Ponnusamy Saravanan |Antonysunil Adaikalakoteswari

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online) Search Issues/Conferences Cite About Our Services Policies Contact Disclaimer SFEBES2025 Poster Presentations Metabolism, Obesity and Diabetes (68 abstracts) Integrated placental multi-omics identifies potential molecular pathways due to maternal B12 deficiency Almost 2 billion adults in the world are overweight, and obesity linked metabolic disorders are a worldwide...

Aug 29, 2024 | nature.com | Rongling Wang |Amanda Coutts |Rubén García-Martín |Matthias Blüher |Christopher J Schofield |Ioannis Kourtzelis | +8 more

AbstractEnhancing thermogenic brown adipose tissue (BAT) function is a promising therapeutic strategy for metabolic disease. However, predominantly thermoneutral modern human living conditions deactivate BAT. We demonstrate that selective adipocyte deficiency of the oxygen-sensor HIF-prolyl hydroxylase (PHD2) gene overcomes BAT dormancy at thermoneutrality. Adipocyte-PHD2-deficient mice maintain higher energy expenditure having greater BAT thermogenic capacity.

Jun 1, 2023 | silverfort.com | Mark Christian

Organizations often encounter issues when trying to implement best practices in mobile device security while also ensuring a seamless user experience. This is because end users can be hesitant to install additional apps on their mobile device, while others engage in risky practices such as jailbreaking or rooting their phones, sometimes even using custom operating systems (OS) and altering the internal read-only memory (ROM).

Jun 1, 2023 | silverfort.com | Mark Christian

June 1st, 2023