Mark Davis

Jul 24, 2024 | nature.com | Vincent van Unen |Steven M. Chirieleison |Joshua Chan |Kathryn E Yost |Zachary M. Sellers |Howard Chang | +5 more

AbstractIn vitro models of autoimmunity are constrained by an inability to culture affected epithelium alongside the complex tissue-resident immune microenvironment. Coeliac disease (CeD) is an autoimmune disease in which dietary gluten-derived peptides bind to the major histocompatibility complex (MHC) class II human leukocyte antigen molecules (HLA)-DQ2 or HLA-DQ8 to initiate immune-mediated duodenal mucosal injury1,2,3,4.

Feb 12, 2024 | nature.com | Ann Park |Justin Q. Gabrielski |Hyoungjun Ham |Jean Michel Chanchu |Aaron R. Morawski |Aiman J. Faruqi | +14 more

Correction to: Nature Immunology https://doi.org/10.1038/s41590-023-01691-y, published online 3 January 2024. In the version of the article initially published, Buket Dalgıç (Department of Pediatric Gastroenterology, Gazi University Faculty of Medicine, Ankara, Turkey) was mistakenly omitted from the author list and has now been added in the HTML and PDF versions of the article. About this articlePark, A.Y., Leney-Greene, M., Lynberg, M. et al.

Jan 3, 2024 | nature.com | Ann Park |Aiman J. Faruqi |Samuel D. Chauvin |Holden T Maecker |Altan Kara |Odile Filhol | +14 more

AbstractPreserving cells in a functional, non-senescent state is a major goal for extending human healthspans. Model organisms reveal that longevity and senescence are genetically controlled, but how genes control longevity in different mammalian tissues is unknown.

Dec 28, 2023 | journals.sagepub.com | Sara Konrath |Alison Jane Martingano |Mark Davis |Fritz Breithaupt

Types of empathy such as concern for others (a form of emotional empathy) and perspective taking (PT; a form of cognitive empathy) have consistently been linked to outcomes such as helping, volunteering (e.g., Ding & Lu, 2016; Yin & Wang, 2023), and more satisfactory social relationships (Davis, 2017). Thus, the finding that dispositional levels of empathic concern (EC) and PT declined among U.S. undergraduates from 1979 to 2009 (Konrath et al., 2011) was noteworthy.

May 24, 2023 | nature.com | Prabhu S Arunachalam |Thomas Hagan |Yupeng Feng |Florian Wimmers |Venkata Viswanadh Edara |Alexandra Lee | +8 more

Addendum to: Nature https://doi.org/10.1038/s41586-021-03791-x Published online 12 July 2021Since the publication of our original article, we have been alerted to a discrepancy between the expression of sex-specific genes in the cellular indexing of transcriptomes and epitopes by sequencing (CITE-seq) and bulk transcriptomics datasets and the reported gender of the subjects, whose transcriptomes were analysed in these datasets.