Martin Prete

Nov 20, 2024 | nature.com | J. Patrick Pett |Kenny Roberts |Raphael Blain |Krzysztof Polanski |Peng He |Chuan Xu | +18 more

AbstractHuman embryonic bone and joint formation is determined by coordinated differentiation of progenitors in the nascent skeleton. The cell states, epigenetic processes and key regulatory factors that underlie lineage commitment of these cells remain elusive.

Nov 20, 2024 | nature.com | Nadav Yayon |Lena Boehme |Brianna T. Wachter |Oren Amsalem |Alexander Predeus |Catherine Tudor | +13 more

AbstractT cells develop from circulating precursor cells, which enter the thymus and migrate through specialized subcompartments that support their maturation and selection1. In humans, this process starts in early fetal development and is highly active until thymic involution in adolescence.

Aug 19, 2024 | nature.com | David Horsfall |Daniela Basurto-Lozada |Kenny Roberts |Martin Prete |Peng He |Josh Moore | +5 more

Multimodal tissue atlasing datasets pose two key challenges for online dissemination and equitable access. First, single-cell RNA-sequencing (scRNA-seq) and spatial transcriptomics data objects are often saved in non-unified sequencing and imaging file formats that perform poorly with web technologies. Second, existing software platforms do not readily support simultaneous browsing of multiple integrated data modalities.

May 22, 2023 | biorxiv.org | Daniela Basurto-Lozada |Kenny Roberts |Martin Prete |David Horsfall

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