Michael Inouye

Dec 5, 2024 | nature.com | Elias Allara |Steven Bell |Dipender Gill |Liam Gaziano |Feiyi Wang |Vinicius Tragante | +30 more

AbstractIron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated with either hepcidin or sTfR concentration, of which 15 previously unreported.

Dec 5, 2024 | nature.com | Elias Allara |Steven Bell |Dipender Gill |Liam Gaziano |Feiyi Wang |Vinicius Tragante | +30 more

AbstractIron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated with either hepcidin or sTfR concentration, of which 15 previously unreported.

Dec 5, 2024 | nature.com | Elias Allara |Steven Bell |Dipender Gill |Liam Gaziano |Feiyi Wang |Vinicius Tragante | +30 more

AbstractIron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation are unclear. In a meta-analysis of 12 cohorts involving 91,675 participants, we found 43 genomic loci associated with either hepcidin or sTfR concentration, of which 15 previously unreported.

Feb 29, 2024 | nature.com | Youwen Qin |Aki S Havulinna |Scott Ritchie |Alex Tokolyi |Yoshiki Vázquez-Baeza |Susan Cheng | +2 more

Correction to: Nature Genetics https://doi.org/10.1038/s41588-021-00991-z, published online 3 February 2022. In the version of the article initially published, the descriptions of two FUT2 genotypes were inverted. In Fig. 4c and Extended Data Fig. 7b and their legends, “rs601338:GG/GA” and “rs601338:AA” previously read “rs601338:AG/AA” and “rs601338:GG”, respectively.

Oct 2, 2023 | itbriefcase.net | Eric Abbruzzese |Jonathan Collins |James Hodgson |Michael Inouye

Key Takeaways From CES 2023 After 2 years of virtual exhibits, halls, and workshops, CES 2023 came back nearly in full swing with over 115,000 attendees. This was mostly a return to normal after a fully virtual show in 2021, and a scaled-back version last year. ABI Research was represented by four analysts—Eric Abbruzzese, Jonathan Collins, James Hodgson, and Michael Inouye—all seasoned CES attendees who have seen this event grow and evolve over the past several years.