Michael Maxwell

1 month ago | physoc.onlinelibrary.wiley.com | Michael Maxwell |Ben Murphy |Fiona McDonald |Ken D. O'Halloran

1 INTRODUCTION Duchenne muscular dystrophy (DMD) is a life-limiting X-linked neuromuscular disease arising from mutations in the DMD gene, leading to the absence of the structural protein dystrophin (Aartsma-Rus et al., 2006; Hoffman et al., 1987).

Sep 8, 2023 | physoc.onlinelibrary.wiley.com | Ken D. O'Halloran |Michael Maxwell |Anthony L. Marullo |Chantelle Hamilton

Introduction Duchenne muscular dystrophy (DMD) is an X-linked fatal neuromuscular disease characterised by neuromuscular dysfunction secondary to dystrophin deficiency (Ervasti, 2007; Hoffman et al., 1987). Substantial diaphragm muscle weakness is a feature of the disease (Burns et al., 2018; Burns, Ali et al., 2017; Burns, Drummond et al., 2019; Burns, Murphy et al., 2019; Burns, Roy et al., 2017).