Anthony L. Marullo

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

Jun 10, 2024 | nature.com | Keith Siew |Charlotte Nelson |Alessandra Grillo |Eliah G. Overbey |JangKeun Kim |Sanghee Yun | +41 more

AbstractMissions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored.

Sep 8, 2023 | physoc.onlinelibrary.wiley.com | Ken D. O'Halloran |Michael Maxwell |Anthony L. Marullo |Chantelle Hamilton

Introduction Duchenne muscular dystrophy (DMD) is an X-linked fatal neuromuscular disease characterised by neuromuscular dysfunction secondary to dystrophin deficiency (Ervasti, 2007; Hoffman et al., 1987). Substantial diaphragm muscle weakness is a feature of the disease (Burns et al., 2018; Burns, Ali et al., 2017; Burns, Drummond et al., 2019; Burns, Murphy et al., 2019; Burns, Roy et al., 2017).

Jun 3, 2023 | physoc.onlinelibrary.wiley.com | Anthony L. Marullo |Ken D. O'Halloran

1 GUT–MUSCLE AXIS Skeletal muscle is the largest metabolic organ making up ∼50% of total body mass (Valentino et al., 2021). While primarily associated with locomotion, skeletal muscle is also responsible for other vital functions, including influencing bone density, insulin-stimulated glucose uptake, fatty acid oxidation and whole-body protein metabolism (Lahiri et al., 2019; Valentino et al., 2021).