Michael Wagner

Nov 13, 2024 | nature.com | Niklas Vockert |Luca Kleineidam |Hartmut Schütze |Renat Yakupov |Josef Priller |Anja Schneider | +11 more

AbstractThe cognitive reserve (CR) hypothesis posits that individuals can differ in how their brain function is disrupted by pathology associated with aging and neurodegeneration. Here, we test this hypothesis in the continuum from cognitively normal to at-risk stages for Alzheimer’s Disease (AD) to AD dementia using longitudinal data from 490 participants of the DELCODE multicentric observational study. Brain function is measured using task fMRI of visual memory encoding.

Apr 12, 2024 | jamanetwork.com | Michael Wagner |Vinod Ravi |Stephanie K. Schaub |Ed Kim

Key PointsQuestion  What are the incidence, presenting characteristics, and change in incidence over time of angiosarcoma in the US? Findings  This cross-sectional study of 19 289 patients with a new diagnosis of angiosarcoma found that the incidence of angiosarcoma is increasing among men and women in the US, with more than 1000 new cases diagnosed per year. This overall increase is associated with a higher incidence rate of secondary breast and chest wall angiosarcomas among women.

Aug 16, 2023 | nature.com | Rafael Campos-Martin |Alexandra Philipsen |Michael Wagner

AbstractObsessive-compulsive disorder (OCD) is a prevalent mental disorder affecting ~2–3% of the population. This disorder involves genetic and, possibly, epigenetic risk factors. The dynamic nature of epigenetics also presents a promising avenue for identifying biomarkers associated with symptom severity, clinical progression, and treatment response in OCD.

Jul 27, 2023 | science.org | Dario Bressan |Kai Wang |Michael Wagner

In the spring of 2020, pressed by internal research staff and with support from the highest levels of the company, Facebook (now Meta) began a collaboration with outside academics to study the 2020 US presidential election. Interest in social media's role in elections came after evidence that the 2016 US election was rife with suspicious and divisive groups targeting swing-state residents on Facebook (1).

Feb 13, 2023 | asa.scitation.org | Michael Wagner

No Access The Journal of the Acoustical Society of America 153, 1108 (2023); https://doi.org/10.1121/10.0017170 Listeners parse the speech signal effortlessly into words and phrases, but many questions remain about how.