Mustafa Buyukozkan

Jun 19, 2023 | nature.com | Fengshen Kuo |Mustafa Buyukozkan |Tricia Park |A. Ari Hakimi |Andrew M. Intlekofer |Jan Krumsiek

AbstractTumour metabolism is controlled by coordinated changes in metabolite abundance and gene expression, but simultaneous quantification of metabolites and transcripts in primary tissue is rare. To overcome this limitation and to study gene–metabolite covariation in cancer, we assemble the Cancer Atlas of Metabolic Profiles of metabolomic and transcriptomic data from 988 tumour and control specimens spanning 11 cancer types in published and newly generated datasets.