Nazish Sayed

Nov 7, 2024 | cell.com | Chun Ching Liu |Mengcheng Shen |Yanxia Liu |Amit Manhas |Shane Zhao |Mao Zhang | +14 more

Keywordsdoxorubicincardio-oncologyCRISPR screeniPSCcarbonic anhydrasecardiomyoctyeglycolysisGet full text accessLog in, subscribe or purchase for full access. References1. Miller, K.D. ∙ Nogueira, L. ∙ Devasia, T. ... Cancer treatment and survivorship statistics, 2022CA Cancer J. Clin. 2022; 72:409-4362. Burridge, P.W. ∙ Li, Y.F. ∙ Matsa, E. ... Human induced pluripotent stem cell-derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicityNat. Med.

Jun 11, 2024 | nature.com | Fei Wu |JangKeun Kim |Cem Meydan |Francine E Garrett-Bakelman |Nazish Sayed |Simon Melov | +4 more

AbstractMicrogravity is associated with immunological dysfunction, though the mechanisms are poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear cells (PBMCs) exposed to short term (25 hours) simulated microgravity, we characterize altered genes and pathways at basal and stimulated states with a Toll-like Receptor-7/8 agonist.