Simon Melov

Jun 11, 2024 | nature.com | Fei Wu |JangKeun Kim |Cem Meydan |Francine E Garrett-Bakelman |Nazish Sayed |Simon Melov | +4 more

AbstractMicrogravity is associated with immunological dysfunction, though the mechanisms are poorly understood. Here, using single-cell analysis of human peripheral blood mononuclear cells (PBMCs) exposed to short term (25 hours) simulated microgravity, we characterize altered genes and pathways at basal and stimulated states with a Toll-like Receptor-7/8 agonist.

Apr 8, 2024 | nature.com | Simon Melov |Lisa M. Ellerby

Judith Campisi, one of the foundational members of the Buck Institute for Research on Aging and an internationally recognized cell biologist for her work on cellular senescence, passed away at her home in Berkeley, California, on 19 January 2024. Judy studied chemistry at the State University of New York at Stony Brook, and obtained her PhD at the same institution.

Jul 19, 2023 | nature.com | Ellen Quardokus |Diane Saunders |Elizabeth Zephyrine McDonough |John Hickey |Christopher Werlein |Hua Tian | +17 more

AbstractMultiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods.