Neal Lakdawala

Aug 15, 2024 | onlinelibrary.wiley.com | Pablo García-Pavía |Neal Lakdawala |Gianfranco Sinagra |Tomás Ripoll-Vera

Introduction Variants in the LMNA gene, which encodes the lamin A and C proteins, are the cause of several clinical syndromes including dilated cardiomyopathy (DCM).1 The pathogenesis of LMNA-related DCM is unclear, but preclinical studies have suggested that several processes are altered in cardiomyocytes, including activation of pro-inflammatory, apoptotic, fibrotic and mitogen-activated protein kinase pathways.2-4 LMNA-related DCM is a progressive and malignant disease characterized by...

Sep 14, 2023 | thelancet.com | KU Leuven |Neal Lakdawala |Charité Universitätsmedizin |Karin Klingel

These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. You can set your browser to block or alert you about these cookies, but some parts of the site will not then work. These cookies do not store any personally identifiable information.