Pablo García-Pavía

Aug 15, 2024 | onlinelibrary.wiley.com | Pablo García-Pavía |Neal Lakdawala |Gianfranco Sinagra |Tomás Ripoll-Vera

Introduction Variants in the LMNA gene, which encodes the lamin A and C proteins, are the cause of several clinical syndromes including dilated cardiomyopathy (DCM).1 The pathogenesis of LMNA-related DCM is unclear, but preclinical studies have suggested that several processes are altered in cardiomyocytes, including activation of pro-inflammatory, apoptotic, fibrotic and mitogen-activated protein kinase pathways.2-4 LMNA-related DCM is a progressive and malignant disease characterized by...

Dec 28, 2023 | jamanetwork.com | Sanjiv Shah |Pablo García-Pavía |Allan Klein

Key PointsQuestion  Does tafamidis, 80 mg, affect cardiac function in patients with transthyretin amyloid cardiomyopathy?

Sep 28, 2023 | onlinelibrary.wiley.com | Perry M. Elliott |Balarama Gundapaneni |Pablo García-Pavía

LETTER TO THE EDITOR Reply to ‘Effects of tafamidis on heart failure hospitalization: The tale of the dog that did not bark’ Perry Elliott,  Corresponding Author Perry Elliott University College London, London, UK Corresponding author.