Neil Wright

2 months ago | nature.com | Neil Wright |Hannah Fry |Yiping Chen |Huaidong Du |Canqing Yu |Dianjianyi Sun | +6 more

AbstractProteomics offers unique insights into human biology and drug development, but few studies have directly compared the utility of different proteomics platforms. We measured plasma levels of 2168 proteins in 3976 Chinese adults using both Olink Explore and SomaScan platforms. The correlation of protein levels between platforms was modest (median rho = 0.29), with protein abundance and data quality parameters being key factors influencing correlation.

Jun 8, 2023 | nature.com | Pek Kei Im |Neil Wright |Yiping Chen |Huaidong Du |Canqing Yu |Robert Clarke | +3 more

Study populationDetails of the CKB study design and methods have been previously reported55. Briefly, 512,724 adults aged 30–79 years were recruited from ten geographically diverse (five rural and five urban) areas across China during 2004–2008.