Olisaemeka Ogbue

Jul 17, 2024 | nature.com | Tariq Kewan |Olisaemeka Ogbue |Sudipto Mukherjee |Anjali Advani |James Cook |Hetty Carraway | +2 more

TO THE EDITOR:Extramedullary deposits of acute myeloid leukemia (eAML), constitute an unusual presentation or complication of AML, which can occur in isolation (isolated eAML) or in the context of a fully-blown leukemic process (synchronous eAML) either at diagnosis or relapse [1,2,3].

Jul 9, 2024 | nature.com | Olisaemeka Ogbue |Tariq Kewan |Valeria Visconte

To the Editor:Large granular lymphocytic leukemia (LGLL) can be defined as a chronic clonal proliferation of either cytotoxic T- (CTLs) or natural killer (NK) cells (T- or NK-LGLL) [1]. In a typical clinical situation, the disease affects elderly patients, who may present with neutropenia (39–62%) and/or anemia (up to 50%) [1], but also with a variety of autoimmune diseases [2].

Jun 20, 2024 | onlinelibrary.wiley.com | Danai Dima |Nerea Lopetegui-Lia |Olisaemeka Ogbue |Bennett Osantowski

1 INTRODUCTION Over the last decade, significant drug advancements have radically shifted the treatment paradigm of melanoma leading to improved patient outcomes.1-3 Immunotherapy (IO) with anti-CTLA4 and anti-PD1 monoclonal antibodies, as well as targeted therapy (TT) with BRAF/MEK inhibitors, demonstrated improved survival of patients with metastatic disease.4-8 More recently, these treatments have been studied in the adjuvant (adj) setting for resected stage III/IV melanoma, also showing...