Paul W. Franks

1 month ago | nature.com | Marta Guasch-Ferré |Clemens Wittenbecher |Ellen E Blaak |Tove Fall |Tine R. Licht |Marie Löf | +11 more

AbstractPrecision nutrition is a vibrant and rapidly evolving field of scientific research and innovation with the potential to deliver health, societal and economic benefits by improving healthcare delivery and policies. Advances in deep phenotyping technologies, digital tools and artificial intelligence have made possible early proof-of-concept research that expands the understanding of within- and between-person variability in responses to diet.

Nov 21, 2024 | nature.com | Paul W. Franks

Sep 25, 2024 | nature.com | Paul W. Franks |Daniel E. Coral

In this issue of Nature Metabolism, Carrasco-Zanini et al. describe sets of modifiable and non-modifiable drivers of human plasma proteins. These findings may inform the design of precision prevention programs and highlight novel therapeutic targets.

Aug 21, 2023 | nature.com | Andrew Brown |Mun-Gwan Hong |Robert Caiazzo |Giuseppe Giordano |Mark Haid |Torben Frøstrup Hansen | +17 more

AbstractWe evaluate the shared genetic regulation of mRNA molecules, proteins and metabolites derived from whole blood from 3029 human donors. We find abundant allelic heterogeneity, where multiple variants regulate a particular molecular phenotype, and pleiotropy, where a single variant associates with multiple molecular phenotypes over multiple genomic regions.