Pedro E. Romero

May 16, 2024 | digitalcommons.library.tmc.edu | Luis 'Speedy Jr' Gonzalez |Luis González |Susan Mosquito |Pedro E. Romero |Yesenia Filio

Home > UTHealth > UTHSPH > Journal Articles > 480 Journal Articles Microbiology Spectrum Infant, Humans, Gastrointestinal Microbiome, Lactoferrin, Peru, Feces, Administration, Oral, RNA, Ribosomal, 16S DOWNLOADS COinS...

Sep 20, 2023 | nature.com | Noelia Maldonado-Pérez |Alessio Bevilacqua |Jhan-Jie Peng |Anouk Lepez |Kung-Chi Kao |Francisco Martin | +4 more

AbstractProtective immunity against pathogens or cancer is mediated by the activation and clonal expansion of antigen-specific naive T cells into effector T cells. To sustain their rapid proliferation and effector functions, naive T cells switch their quiescent metabolism to an anabolic metabolism through increased levels of aerobic glycolysis, but also through mitochondrial metabolism and oxidative phosphorylation, generating energy and signalling molecules1,2,3.