Peng Liao

Jun 13, 2024 | nature.com | Peng Ding |Delin Liu |Peng Liao |Minghao Zheng |Youshui Gao |Changqing Zhang | +1 more

AbstractInteractions between osteolineage cells and myeloid cells play important roles in maintaining skeletal homeostasis. Herein, we find that osteolineage cells transfer mitochondria to myeloid cells. Impairment of the transfer of mitochondria by deleting MIRO1 in osteolineage cells leads to increased myeloid cell commitment toward osteoclastic lineage cells and promotes bone resorption.

May 14, 2024 | nature.com | Peng Liao |Minghao Zheng

AbstractMitochondria, with their intricate networks of functions and information processing, are pivotal in both health regulation and disease progression. Particularly, mitochondrial dysfunctions are identified in many common pathologies, including cardiovascular diseases, neurodegeneration, metabolic syndrome, and cancer. However, the multifaceted nature and elusive phenotypic threshold of mitochondrial dysfunction complicate our understanding of their contributions to diseases.

Mar 21, 2024 | nature.com | Peng Liao |Weiguo Zou |Peng Ding |Changqing Zhang |Delin Liu |Minghao Zheng | +2 more

AbstractTranscortical vessels (TCVs) provide effective communication between bone marrow vascular system and external circulation. Although osteocytes are in close contact with them, it is not clear whether osteocytes regulate the homeostasis of TCVs. Here, we show that osteocytes maintain the normal network of TCVs by transferring mitochondria to the endothelial cells of TCV. Partial ablation of osteocytes causes TCV regression.

Nov 10, 2023 | pubs.rsc.org | Peng Liao |Xiang Yu |Jiaqi He |Xin Zhang

High energy density zinc ion capacitors based on 3D porous free-standing defect reduced graphene oxide hydrogel cathodes Zinc ion capacitors (ZICs) have shown promising potential in breaking the energy density ceiling of traditional supercapacitors (SCs) using appropriate device design. Nevertheless, a significant challenge in the advance of ZIC positive electrode materials with excellent conductivity, high specific capacitance, and reliable cycle stability remains.

Aug 3, 2023 | frontiersin.org | Silvia Turroni |Peng Liao |Hang Yu

1. Background Berberine (BBR) is able to be extracted from the roots and rhizomes of a variety of medicinal plants, such as Berberis kansuensis C.K. Schneid. (Berberidaceae), Coptis chinensis Franch. (Ranunculaceae), Coscinium fenestratum (Goetgh.) Colebr. (Menispermaceae), Argemone mexicana L. (Papaveraceae), and Phellodendron amurense Rupr. (Rutaceae),whose chemical composition is an isoquinoline alkaloid (1).