Pol Alentorn-Moron

Oct 7, 2024 | nature.com | Nuria Hermosilla-Albala |Claudia Fontsere |Joanna L. Kelley |Pol Alentorn-Moron |Esther Lizano |Izeni Farias | +4 more

AbstractDespite showing the greatest primate diversity on the planet, genomic studies on Amazonian primates show very little representation in the literature. With 48 geolocalized high coverage whole genomes from wild uakari monkeys, we present the first population-level study on platyrrhines using whole genome data.

May 23, 2024 | nature.com | Luis Ferrández-Peral |Claudia Fontsere |Merve Ceylan |Giovanni Lara |Jacques Dainat |Arthur O. Zalevsky | +8 more

AbstractSLC22A10 is an orphan transporter with unknown substrates and function. The goal of this study is to elucidate its substrate specificity and functional characteristics. In contrast to orthologs from great apes, human SLC22A10, tagged with green fluorescent protein, is not expressed on the plasma membrane. Cells expressing great ape SLC22A10 orthologs exhibit significant accumulation of estradiol-17β-glucuronide, unlike those expressing human SLC22A10.