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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Zhiming Hu
RESULTSThanks to two critical boundary values of fiber winding angles θ1 and θ2 unprecedentedly discovered in this work (Fig. 1E), HAFMS-TSAs can generate diverse controllable, complex shape transformations, which are shown in Fig. 1D.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Grischa Y. Chen
AbstractAnimals evolved two defense strategies to survive infections. Antagonistic strategies include immune resistance mechanisms that operate to kill invading pathogens. Cooperative or physiological defenses mediate host adaptation to the infected state, limiting physiological damage and disease, without killing the pathogen, and have been shown to cause asymptomatic carriage and transmission of lethal pathogens.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Huan-Min Liu
MATERIALS AND METHODSAnimalsMale Sprague-Dawley rats weighing 180 to 220 g were obtained from the Institute of Experimental Animals of Sun Yat-sen University. All animals were housed at 24° ± 1°C and 50 to 60% humidity with a 12-hour light/12-hour dark cycle and were provided food and water ad libitum.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Lulu Yao
Electrochemical characterizationIn structural supercapacitors, the electrolyte was typically a uniform composite directed by vacuum infusion to flow through the electrodes and separator and then solidified together. The epoxy resin is essential to maintain rigidity for load support, but it is electrochemically inert and limits surface adsorption and interfacial redox reactions that dictate the cell capacitance and energy storage capacity.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Taki Nishimura |Gianmarco Lazzeri
AHATG3 regulates the organization of the ATG3~LC3 conjugate on membranesWe wondered how mutations in the AH would affect its dynamics and the organization of the ATG3~LC3 conjugate. We created an atomistic model of the first 24 residues of ATG3 as an α-helix and inserted it into a lipid bilayer (Fig. 5A). Studying the helix in isolation enabled us to focus on the helix-membrane interactions and accumulate longer simulation times.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Hongguang Liu
AbstractMarine-terrestrial transition represents an important aspect of organismal evolution that requires numerous morphological and genetic innovations and has been hypothesized to be caused by geological changes. We used talitrid crustaceans with marine-coastal-montane extant species at a global scale to investigate the marine origination and terrestrial adaptation.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Jun Xu
AbstractThe trade-off between activity and stability of oxygen evolution reaction (OER) catalysts in proton exchange membrane water electrolyzer (PEMWE) is challenging. Crystalline IrO2 displays good stability but exhibits poor activity; amorphous IrOx exhibits outstanding activity while sacrificing stability. Here, we combine the advantages of these two materials via a lattice water–incorporated iridium oxide (IrOx·nH2O) that has short-range ordered structure of hollandite-like framework.
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Zhiqiang Hu |Yingchao Xie
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Jia-Ren Lin |Emmalyn Lecky |Atreyi Mukherji |Michael Yorsz | +8 more
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Jun 23, 2023 | 
science.org | Zhenzhen Wang |Queenie Chang |Yin Zhai
DISCUSSIONOur data identify a drug, DEQ (fig. S2D), that targets the σS response, a mutagenesis network hub (11), and inhibits cipro antibiotic–induced mutagenesis (Fig. 1 and figs. S2 and S3), and identify the step at which it acts (Figs. 2 and 3, A to C) in a defined pathway (35, 39) of cipro-induced mutagenic DNA break repair. DEQ blocks induction of the stringent starvation stress response (Fig. 3) after formation of its inducer, ROS (39) (Fig. 2B), and before stringent induction (Fig.
