Richard Dinga

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Extreme deviations from the normative model reveal cortical heterogeneity and associations with negative symptom severity in first-episode psychosis from the OPTiMiSE and GAP studies | Translational Psychiatry

Dec 1, 2023 | nature.com | Celso Arango |Richard Dinga |Birte Glenthøj |René S. Kahn |Robin Murray |Carmine Pariante | +2 more

AbstractThere is currently no quantifiable method to predict long-term clinical outcomes in patients presenting with a first episode of psychosis. A major barrier to developing useful markers for this is biological heterogeneity, where many different pathological mechanisms may underly the same set of symptoms in different individuals.

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