Rui Guo

Jan 3, 2025 | science.org | Zhen Ma |Ming Li |Rui Guo |Yu Tian |Yongbin Zheng |Bingxin Huang | +13 more

Research ArticleAPPLIED SCIENCES AND ENGINEERINGINTRODUCTIONIschemic heart disease remains a leading cause of mortality and disability worldwide, affecting approximately 126 million people globally (1, 2). Myocardial infarction (MI) is the most severe form of ischemic heart disease (3). Now, adverse ventricular remodeling and heart failure following MI continue to be the primary contributors to patient mortality (4).

May 20, 2024 | dovepress.com | Meng Wu |Shuang Wu |Rui Guo

IntroductionBreast cancer is a complex and heterogeneous disease that remains a significant public health issue.

May 15, 2024 | nature.com | Rui Guo

AbstractEpstein-Barr virus (EBV) uses a biphasic lifecycle of latency and lytic reactivation to infect >95% of adults worldwide. Despite its central role in EBV persistence and oncogenesis, much remains unknown about how EBV latency is maintained. We used a human genome-wide CRISPR/Cas9 screen to identify that the nuclear protein SFPQ was critical for latency.

Dec 22, 2023 | jnm.snmjournals.org | Ying Miao |Runhua Feng |Teng Yu |Rui Guo

fibroblast activation protein inhibitorPET/CTneoadjuvant chemotherapylocally advanced gastric cancerIn patients with locally advanced gastric cancer (LAGC) before radical surgery, neoadjuvant chemotherapy (NAC) is increasingly being applied because it may help control focal lesions, downstage tumors, increase R0 resection rates, and improve the disease-free and overall survival of patients (1–4). However, the role of preoperative NAC in LAGC remains controversial (5,6).

Sep 9, 2023 | onlinelibrary.wiley.com | Yang Lyu |Shandong Laboratory |Green Manufacturing |Rui Guo

Conflict of Interest The authors declare no conflict of interest.