Ruth Costello

Nov 19, 2024 | nature.com | Ruth Costello |Emily Herrett |Amir Mehrkar |Laurie Tomlinson |Christopher T. Rentsch

AbstractBiological evidence suggests ursodeoxycholic acid (UDCA)—a common treatment of cholestatic liver disease—may prevent severe COVID-19 outcomes. We aimed to compare the hazard of COVID-19 hospitalisation or death between UDCA users versus non-users in a population with primary biliary cholangitis (PBC) or primary sclerosing cholangitis (PSC).

Oct 16, 2024 | bmjopen.bmj.com | Ruth Costello |Lars Pedersen |Alasdair Henderson |John Tazare

ExposuresThe primary exposure was socioeconomic deprivation which was measured by proxy. In England, deprivation was measured using quintiles of the patient-level Index of Multiple Deprivation (IMD) 2019.23 IMD is a lower super output area level (comprising 400 to 1200 people) which is a measure of relative deprivation based on a person’s postcode. The IMD score is based on indicators related to income, education, employment, health, crime, barriers to housing and services and living environment.

May 9, 2024 | medrxiv.org | Ruth Costello |Alasdair Henderson |John Tazare |Lars Bo Pedersen

REC has personal shares in AstraZeneca (AZ) unrelated to this work. BMK is also employed by NHS England (all declarations are openly available at: https://www.whopaysthisdoctor.org/doctor/491/active). JFH has grant funding from UKRI and the Wellcome Trust, has a patent with Juli Health unrelated to this work and has received consultancy fees from Juli Health and the Wellcome Trust unrelated to this work.

Jun 29, 2023 | tinyurl.com | S List |Ruth Costello |John Tazare |Dominik M. Piehlmaier

SummaryThe COVID-19 pandemic disrupted healthcare and may have impacted ethnic inequalities in healthcare. We aimed to describe the impact of pandemic-related disruption on ethnic differences in clinical monitoring and hospital admissions for non-COVID conditions in England.