Alasdair Henderson

Nov 2, 2024 | jacc.org | Shingo Matsumoto |Pardeep S. Jhund |Alasdair Henderson |Johann Bauersachs

IntroductionKidney dysfunction often leads to reluctance to continue disease-modifying therapies in patients with heart failure (HF).

Oct 16, 2024 | bmjopen.bmj.com | Ruth Costello |Lars Pedersen |Alasdair Henderson |John Tazare

ExposuresThe primary exposure was socioeconomic deprivation which was measured by proxy. In England, deprivation was measured using quintiles of the patient-level Index of Multiple Deprivation (IMD) 2019.23 IMD is a lower super output area level (comprising 400 to 1200 people) which is a measure of relative deprivation based on a person’s postcode. The IMD score is based on indicators related to income, education, employment, health, crime, barriers to housing and services and living environment.

Oct 11, 2024 | jacc.org | Jawad H. Butt |Alasdair Henderson |Pardeep S. Jhund |Brian Claggett

Introduction Aldosterone is secreted by the adrenal glands and regulated by circulating angiotensin II and serum potassium concentration, and the deleterious consequences of excessive production of this hormone (and mineralocorticoid receptor overactivation) on the heart, vasculature, and kidney are well-established.1-5 However, aldosterone synthase is also expressed in adipocytes, which can secrete aldosterone, and angiotensin II is produced in adipose tissue and stimulates the production of...

Aug 31, 2024 | onlinelibrary.wiley.com | Shingo Matsumoto |Alasdair Henderson |Li Shen |Toru Kondo

Supporting Information Filename Description ejhf3383-sup-0001-Supinfo.docxWord 2007 document , 5.9 MB Data S1. Supporting Information. References 1, , , , , , et al. 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: Developed by the Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). With the special contribution of the Heart Failure Association (HFA) of the ESC.

May 17, 2024 | thelancet.com | Alasdair Henderson |Keppel Street |Ben Butler-Cole |John Tazare

Research in contextWe searched PubMed for research published between 1st January 2020 and 1st November 2023, published in English, for the Title/Abstract terms (Post COVID-19 Condition OR PCC OR post-acute-covid-19 OR PASC OR long covid) AND (Electronic Health Records OR routinely collected health∗) AND (prevalence OR descriptive OR describe).