Samuel J DePalma

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Induced pluripotent stem cell-derived cardiomyocyte in vitro models: benchmarking progress and ongoing challenges - Nature Methods

Nov 8, 2024 | nature.com | Jourdan Ewoldt |Samuel J DePalma |Maggie E. Jewett |Lihua Lou |Micheal A. McLellan |Jin He | +7 more

AbstractRecent innovations in differentiating cardiomyocytes from human induced pluripotent stem cells (hiPSCs) have unlocked a viable path to creating in vitro cardiac models. Currently, hiPSC-derived cardiomyocytes (hiPSC-CMs) remain immature, leading many in the field to explore approaches to enhance cell and tissue maturation.

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