Sara Hägg

3 weeks ago | nature.com | Chiara Herzog |Kejun Ying |Raghav Sehgal |Waylon J. Hastings |Alexander Tyshkovskiy |Sara Hägg | +19 more

On 1–2 November 2024, the annual Biomarkers of Aging conference welcomed academic and industry scientists, and partners from governmental and nongovernmental organizations, to Harvard Medical School in Boston, USA, to discuss new insights into measuring and monitoring human aging, with the aim of clinical translation. In this Meeting Report, we summarize the conference and offer potential future directions for the Biomarkers of Aging Consortium and the longevity science community at large.

Jun 23, 2024 | nature.com | Aoxing Liu |Sara Hägg

AbstractShort-term mortality risk, which is indicative of individual frailty, serves as a marker for aging. Previous age clocks focused on predicting either chronological age or longer-term mortality. Aging clocks predicting short-term mortality are lacking and their algorithmic fairness remains unexamined.

Feb 14, 2024 | nature.com | Chiara Herzog |Jesse R. Poganik |Kejun Ying |Daniel Belsky |Albert T. Higgins-Chen |Alan Cohen | +12 more

AbstractThe search for biomarkers that quantify biological aging (particularly ‘omic’-based biomarkers) has intensified in recent years. Such biomarkers could predict aging-related outcomes and could serve as surrogate endpoints for the evaluation of interventions promoting healthy aging and longevity. However, no consensus exists on how biomarkers of aging should be validated before their translation to the clinic.

Dec 25, 2023 | inverse.com | Sara Hägg

As we journey through life, the risk of developing chronic diseases, including cancer, heart disease, and neurological disorders, increases significantly. However, while we all grow older chronologically at the same pace, biologically, our clocks can tick faster or slower. Relying solely on chronological age — the number of years since birth — is inadequate to measure the body’s internal biological age. This discrepancy has prompted scientists to find ways to determine a person’s biological age.

Nov 11, 2023 | scroll.in | Sara Hägg

As we journey through life, the risk of developing chronic diseases, including cancer, heart disease and neurological disorders, increases significantly. However, while we all grow older chronologically at the same pace, biologically, our clocks can tick faster or slower. Relying solely on chronological age – the number of years since birth – is inadequate to measure the body’s internal biological age. This discrepancy has prompted scientists to find ways to determine a person’s biological age.