Seung Jae Kim

Feb 20, 2024 | nature.com | Seung Jae Kim |Minh-Duy Phan |Matthew Sullivan |Katharine M. Irvine |Scott A. Beatson |Matthew Sweet | +4 more

AbstractBacteria adapt to selective pressure in their immediate environment in multiple ways. One mechanism involves the acquisition of independent mutations that disable or modify a key pathway, providing a signature of adaptation via convergent evolution. Extra-intestinal pathogenic Escherichia coli (ExPEC) belonging to sequence type 95 (ST95) represent a global clone frequently associated with severe human infections including acute pyelonephritis, sepsis, and neonatal meningitis.