
Shahzad Raza
Articles
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2 weeks ago |
cgtlive.com | Shahzad Raza |Noah Stansfield
This is the second part of an interview with Shahzad Raza, MD. For the first part, click here. “This is very different than continuing to bring patients to the clinic every week do therapy. A treatment holiday—freedom from more treatments —at least for our timeline, I think would be an important point for these patients.
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3 weeks ago |
cgtlive.com | Shahzad Raza |Noah Stansfield
“So far, the data is quite promising to share that this is very safe... I'm hoping that by the next 6 months, we will have much more mature data, more patients enrolled... The phase 1b and phase 2a is quite exciting. This data does show it's a safe drug and can be given safely to the patients.”Relapsed/refractory (r/r) light chain (AL) amyloidosis remains a particularly difficult disease to treat, and as such great unmet need exists for patients in this population.
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1 month ago |
nature.com | Oren Pasvolsky |Lei Feng |James Davis |Aimaz Afrough |Mariola Vazquez-Martinez |Utkarsh Goel | +22 more
AbstractTeclistamab, a BCMA-directed bispecific antibody, received regulatory approval for relapsed/refractory multiple myeloma (RRMM) based on the MajesTEC-1 study. Despite the fact that myeloma is primarily a cancer of elderly adults, only 15% of MajesTEC-1 participants (n = 24) were ≥75 years old. In this multicenter retrospective study, we report real-world outcomes of a large cohort of older RRMM patients treated with teclistamab.
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Dec 4, 2024 |
nature.com | Maximilian Merz |Danai Dima |Nausheen Ahmed |Friedrich Stölzel |Fabian Müller |Aina Oliver-Caldes | +12 more
AbstractDespite the astonishing outcomes after chimeric antigen receptor (CAR) T-cell therapy for relapsed refractory multiple myeloma (RRMM), most patients eventually relapse. There are only limited data available on salvage therapies following relapse after BCMA-directed CAR T-cell therapy.
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Dec 4, 2024 |
nature.com | Maximilian Merz |Danai Dima |Nausheen Ahmed |Friedrich Stölzel |Fabian Müller |Aina Oliver-Caldes | +12 more
AbstractDespite the astonishing outcomes after chimeric antigen receptor (CAR) T-cell therapy for relapsed refractory multiple myeloma (RRMM), most patients eventually relapse. There are only limited data available on salvage therapies following relapse after BCMA-directed CAR T-cell therapy.
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