Shingo Kajimura

Oct 20, 2024 | febs.onlinelibrary.wiley.com | Matthew Sinton |Shingo Kajimura

Introduction The adipose tissue, which was once thought of as an inert energy storage facility, is now understood to exert profound effects on energy balance, through both endocrine signalling and regulation of organismal behaviour.

Sep 3, 2024 | jci.org | Evan Rosen |Shingo Kajimura

Uncovering inflammation in adipose tissueThe association between obesity and diabetes has been recognized since ancient times; as early as the fifth century BCE, the Indian physician Sushruta linked diabetes in wealthy people to excessive consumption of grains and sweets (1).

Aug 28, 2024 | nature.com | Ichitaro Abe |JING CHEN |Linna Zhou |Noelia Martínez-Sánchez |Michael L. Dustin |Cheng Zhan | +5 more

AbstractHuman mutations in neuropeptide Y (NPY) have been linked to high body mass index but not altered dietary patterns1. Here we uncover the mechanism by which NPY in sympathetic neurons2,3 protects from obesity.