Shitong Xiang

Jul 14, 2024 | nature.com | Runye Shi |Shitong Xiang |Tianye Jia |Trevor Robbins |Jujiao Kang |Tobias Banaschewski | +21 more

AbstractAdolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity remains poorly understood.

Jul 2, 2024 | nature.com | Yang Guo |Chao Xie |Shitong Xiang |Tianye Jia |Lin Lu |Yan Sun | +6 more

Brain function is vulnerable to the consequences of inadequate sleep, an adverse trend that is increasingly prevalent. The REM sleep phase has been implicated in coordinating various brain structures and is hypothesized to have potential links to brain variability. However, traditional imaging research have encountered challenges in attributing specific brain region activity to REM sleep, remained understudied at the whole-brain connectivity level. Through the spilt-night paradigm, distinct patterns of REM sleep phases were observed among the full-night sleep group (n = 36), the early-night deprivation group (n = 41), and the late-night deprivation group (n = 36). We employed connectome-based predictive modeling (CPM) to delineate the effects of REM sleep deprivation on the functional connectivity of the brain (REM connectome) during its resting state. The REM sleep-brain connectome was characterized by stronger connectivity within the default mode network (DMN) and between the DMN and visual networks, while fewer predictive edges were observed. Notably, connections such as those between the cingulo-opercular network (CON) and the auditory network, as well as between the subcortex and visual networks, also made significant contributions. These findings elucidate the neural signatures of REM sleep loss and reveal common connectivity patterns across individuals, validated at the group level.

Sep 17, 2023 | psiquiatria.com | Shitong Xiang |Tianye Jia

El consumo de cigarrillos entre los adolescentes jóvenes es un problema acuciante de salud pública. Sin embargo, los mecanismos neuronales que subyacen al inicio y mantenimiento del tabaquismo durante la adolescencia, especialmente las posibles interacciones causales entre el desarrollo cerebral alterado y el comportamiento de fumar, siguen siendo difíciles de alcanzar.

Aug 15, 2023 | nature.com | Shitong Xiang |Tianye Jia |Tobias Banaschewski |Gareth Barker |Christian Büchel |Sylvane Desrivières | +15 more

AbstractSmoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal interactions between altered brain development and smoking behaviour, remain elusive.

Aug 9, 2023 | nature.com | Shitong Xiang |Xuerui Peng |Tobias Banaschewski |Gareth Barker |Christian Büchel |Herta Flor | +17 more

Correction to: Nature Medicine https://doi.org/10.1038/s41591-023-02317-4. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M.