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2 months ago | 
nature.com | Qingyang Li |Miao Cao |Dan Stein |Barbara Sahakian |Tianye Jia |Christelle Langley | +22 more
AbstractLaboratory studies show brain maturation involves synaptic pruning and cognitive development. Human studies suggest links between early cognitive performance and later mental health, but inconsistencies remain. It is unclear if specific brain regions mediate this relationship, and the molecular underpinnings are not well understood.
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Jan 9, 2025 | 
nature.com | Xinyang Yu |Zuo Zhang |Moritz Herle |Tobias Banaschewski |Gareth Barker |Herta Flor | +16 more
AbstractUnhealthy eating, a risk factor for eating disorders (EDs) and obesity, often coexists with emotional and behavioral problems; however, the underlying neurobiological mechanisms are poorly understood. Analyzing data from the longitudinal IMAGEN adolescent cohort, we investigated associations between eating behaviors, genetic predispositions for high body mass index (BMI) using polygenic scores (PGSs), and trajectories (ages 14–23 years) of ED-related psychopathology and brain maturation.
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Jul 14, 2024 | 
nature.com | Runye Shi |Shitong Xiang |Tianye Jia |Trevor Robbins |Jujiao Kang |Tobias Banaschewski | +21 more
AbstractAdolescents exhibit remarkable heterogeneity in the structural architecture of brain development. However, due to limited large-scale longitudinal neuroimaging studies, existing research has largely focused on population averages, and the neurobiological basis underlying individual heterogeneity remains poorly understood.
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Jul 1, 2024 | 
nature.com | Tobias Banaschewski |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz |Rüdiger Brühl | +9 more
AbstractPerseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take several ruminative response styles, that diverge in manifestations, severity, and mental health outcomes. Still, prospective ruminative phenotypes remain elusive insofar.
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Jun 17, 2024 | 
nature.com | Teresa Del Bianco |Meng-Chuan Lai |Tony Charman |Tobias Banaschewski |Jan Buitelaar
AbstractFace-processing timing differences may underlie visual social attention differences between autistic and non-autistic people, and males and females. This study investigates the timing of the effects of neurotype and sex on face-processing, and their dependence on age.
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Oct 19, 2023 | 
nature.com | Tobias Banaschewski |Gareth Barker |Sylvane Desrivières |Herta Flor |Penny Gowland |Andreas Heinz | +17 more
AbstractThe cerebral ventricles are recognized as windows into brain development and disease, yet their genetic architectures, underlying neural mechanisms and utility in maintaining brain health remain elusive. Here we aggregated genetic and neuroimaging data from 61,974 participants (age range, 9 to 98 years) in five cohorts to elucidate the genetic basis of ventricular morphology and examined their overlap with neuropsychiatric traits.
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Sep 22, 2023 | 
nature.com | Feng Chen |Meiyun Wang |Xiaochu Zhang |Wen Qin |Feng Liu |Qiang Xu | +24 more
AbstractExposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental process. However, environment-brain-personality covariation patterns and their mediation relationships remain unclear.
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Aug 23, 2023 | 
jamanetwork.com | Gunter Schumann |Clinical Neuroscience |Charité Universitätsmedizin Berlin |Tobias Banaschewski
Addressing Global Environmental Challenges to Mental Health Using Population Neuroscience: A Review
Abstract
Importance
Climate change, pollution, urbanization, socioeconomic inequality, and psychosocial effects of the COVID-19 pandemic have caused massive changes in environmental conditions that affect brain health during the life span, both on a population level as well as on the level of the individual.
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Aug 15, 2023 | 
nature.com | Shitong Xiang |Tianye Jia |Tobias Banaschewski |Gareth Barker |Christian Büchel |Sylvane Desrivières | +15 more
AbstractSmoking of cigarettes among young adolescents is a pressing public health issue. However, the neural mechanisms underlying smoking initiation and sustenance during adolescence, especially the potential causal interactions between altered brain development and smoking behaviour, remain elusive.
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Aug 9, 2023 | 
nature.com | Shitong Xiang |Xuerui Peng |Tobias Banaschewski |Gareth Barker |Christian Büchel |Herta Flor | +17 more
Correction to: Nature Medicine https://doi.org/10.1038/s41591-023-02317-4. Published online 24 April 2023. In the version of this article initially published, the STRATIFY data also included cohort data from the ESTRA consortium, though this was not acknowledged in the author list and the section in Methods on the Stratify dataset. The Methods are now updated, and the author list is amended to combine the STRATIFY and ESTRA consortium names and to include the following authors: Marina Bobou, M.
