Shiyu Sun

Aug 30, 2023 | nature.com | Meng Huang |Shiyu Sun |Li Shen |John M. Ballato

AbstractRaman scattering provides a convenient mechanism to generate or amplify light at wavelengths where gain is not otherwise available. When combined with recent advancements in high-power fiber lasers that operate at wavelengths ~2 μm, great opportunities exist for Raman systems that extend operation further into the mid-infrared regime for applications such as gas sensing, spectroscopy, and biomedical analyses.

Jul 25, 2023 | onlinelibrary.wiley.com | Mengjie Liu |Chaofan Li |Jingkun Qu |Shiyu Sun

Baicalein inhibits LEP secretion to downregulate PD-L1 expression and enhance T-cell killing effects Our previous study showed that the IC50 values for baicalein for MDA-MB-231 at 24, 48, and 72 h were 79.12/50.10/34.77 μM and for MCF-7 at 24, 48, and 72 h were 49.76/43.73/39.44 μM, respectively.17 To exclude the obvious cytotoxic effect of baicalein on cancer cells, a concentration ≤40 μM was adopted to verify PD-L1 regulation of baicalein in a tumor microenvironment.