Simone M. Schoenwaelder

3 weeks ago | nature.com | Rhyll E. Smythe |Eduardo A. Albornoz |Jonathan E Noonan |Trent M Woodruff |André Samson |Simone M. Schoenwaelder | +3 more

AbstractMicroangiopathy is a major complication of SARS-CoV-2 infection and contributes to the acute and chronic complications of the disease1. Endotheliopathy and dysregulated blood coagulation are prominent in COVID-19 and are considered to be major causes of microvascular obstruction1,2. Here we demonstrate extensive endothelial cell (EC) death in the microvasculature of COVID-19 organs.