Stefano Freddi

Featured in: Favicon

Articles

TBC1 domain-containing proteins are frequently involved in triple-negative breast cancers in connection with the induction of a glycolytic phenotype - Cell Death & Disease

Sep 3, 2024 | nature.com | Daniele Avanzato |Flavia Martino |Emanuela Pupo |Valentina Audrito |Stefano Freddi |Giovanni Bertalot | +3 more

AbstractMetabolic plasticity is a hallmark of cancer, and metabolic alterations represent a promising therapeutic target. Since cellular metabolism is controlled by membrane traffic at multiple levels, we investigated the involvement of TBC1 domain-containing proteins (TBC1Ds) in the regulation of cancer metabolism. These proteins are characterized by the presence of a RAB-GAP domain, the TBC1 domain, and typically function as attenuators of RABs, the master switches of membrane traffic.
Microbial biofilms on macroalgae harbour diverse integron gene cassettes

Mar 15, 2024 | microbiologyresearch.org | Stefano Freddi |Vaheesan Rajabal |Sasha G. Tetu |Michael R. Gillings

Article metrics loading... /content/journal/micro/10.1099/mic.0.001446Download as PowerPoint /deliver/fulltext/micro/170/3/mic001446.html?itemId=/content/journal/micro/10.1099/mic.0.001446&mimeType=html&fmt=ahah References Ghaly TM, Gillings MR, Penesyan A, Qi Q, Rajabal V et al. The natural history of integrons. Microorganisms 2021; 9:2212 [View Article] [PubMed][Google Scholar] Recchia GD, Hall RM. Gene cassettes: a new class of mobile element.

Try JournoFinder For Free

Search and contact over 1M+ journalist profiles, browse 100M+ articles, and unlock powerful PR tools.