Emily Guo

Oct 1, 2024 | biorxiv.org | John Richardson |Emily Guo |Ryan M. Wyllie |Paul Jensen

AbstractStreptococcus pneumoniae is an important human pathogen that normally resides in the human nasopharynx. Competence mediated bacteriocin expression by S pneumoniae plays a major role in both the establishment and persistence of colonization on this polymicrobial surface. Over 20 distinct bacteriocin loci have been identified in pneumococcal genomes, but only a small number have been characterized phenotypically. In this work, we demonstrate that 3/4th of S.

Mar 9, 2024 | biorxiv.org | Emily Guo |Steven Z. Chou |María Lara-Tejero |Jorge Galán

AbstractThe bacterial pathogen Salmonella spp. modulates cellular processes by delivering effector proteins through its type III secretion systems. Among these effectors, SipA facilitates bacterial invasion and promotes intestinal inflammation. The mechanisms by which this effector carries out these functions are incompletely understood although SipA's ability to modulate actin dynamics is central to some of these activities. Here we report the cryo-EM structure of SipA bound to filamentous actin.

Feb 27, 2024 | onlinelibrary.wiley.com | Emily Guo |Heather Richmond |Joan K. Fernandez

REFERENCES 1, . The diagnostic value of café-au-lait macules. J Am Acad Dermatol. 1999; 40(6): 877–890. 2. The diagnostic and clinical significance of café-au-lait macules. Pediatr Clin North Am. 2010; 57(5): 1131–1153. 3 Melanocytic neoplasms. In: Practical dermatopathology. 3 ed. Philadelphia: Elsevier; 2021. p. 289. 4, . The incidence and significance of birthmarks in a cohort of 4,641 newborns. Pediatr Dermatol. 1983; 1: 58–68. 5. Diagnostic value of the cafe-au-lait spot in children.

Oct 17, 2023 | onlinelibrary.wiley.com | Taryn N. Murray |Emily Guo |Heather Richmond |Paul Friedman

INTRODUCTION Scars are a common dermatologic complaint that can adversely affect an individual's quality of life. With diverse etiologies and types of scars, treatment is often challenging. Myriad treatment options exist ranging from topical medications to surgical revision, however, no scar treatment has been as revolutionary as lasers.