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1 month ago | 
designtechworld.medium.com | Sumit Kumar Singh
Angular has long relied on RxJS and Observables for reactive state management. But with the release of Angular v16 and beyond, Angular introduced Signals — a simpler, more predictable reactivity model inspired by SolidJS and Svelte. This tutorial walks you through creating Angular components using Signals and shows how they can simplify change detection and state flow. A Signal is a reactive primitive that holds a value and notifies listeners when it changes. Think of it as a reactive variable.
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1 month ago | 
sumitkumarsingh.medium.com | Sumit Kumar Singh
Over the past few months, I’ve been holding discussions and workshops with CXOs, business and AI product leaders and mapping how the world’s most successful AI companies are building, scaling, and winning — from foundational models to vertical AI workflows. Massive thanks to our amazing global community at PM Mixer — The product club and AceAi-InterviewClub.
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1 month ago | 
sumitkumarsingh.medium.com | Sumit Kumar Singh
A curated guide to the most talked-about and sometimes misunderstood AI terms flooding X (Twitter), LinkedIn, and product decks in 2025 — with real-world examples. Definition: A method that combines a language model with a search system to fetch relevant information from a database or documents and use it in generating more accurate and fact-based responses. Example: A chatbot answering legal queries by pulling clauses from a law firm’s internal database.
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1 month ago | 
sumitkumarsingh.medium.com | Sumit Kumar Singh
Here’s a handy guide for anyone trying to make sense of all the jargon in the fast-moving world of Artificial Intelligence, complete with simple examples. If you feel, I missed something, do add it in the comments and I’ll update this glossary. AI that can understand, learn, and apply knowledge in any domain like a human. Example: An AGI could switch from coding to painting to cooking without retraining. AI that acts on your behalf to complete tasks.
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Dec 29, 2024 | 
analyticalsciencejournals.onlinelibrary.wiley.com | Jayanth Venkatarama Reddy |Thomas Leibiger |Sumit Kumar Singh
Supporting Information Filename Description bit28916-sup-0001-Supplementary_information.docx2.3 MB Supporting information. References , , , et al. 2019. “Mechanistic Reconstruction of Glycoprotein Secretion Through Monitoring of Intracellular N-Glycan Processing.” Science Advances 5, no. 11: eaax8930. https://doi.org/10.1126/sciadv.aax8930. , and . 2016. “Glycosylation of Monoclonal Antibody Products: Current Status and Future Prospects.” Biotechnology Progress 32, no.
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Aug 31, 2024 | 
designtechworld.medium.com | Sumit Kumar Singh
In JavaScript, understanding the concepts of and is fundamental to grasping how inheritance works in the language. These two concepts are often confused, but they serve different purposes and operate in distinct ways within the prototype chain. Let's dive deep into each concept, exploring their roles, relationships, and how they contribute to JavaScript's inheritance mechanism. JavaScript is a prototype-based language, meaning that objects can inherit properties and methods from other objects.
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Aug 30, 2024 | 
medium.com | Sumit Kumar Singh
In JavaScript, the ?? (Nullish Coalescing Operator) and || (Logical OR Operator) are both used to provide default values or short-circuit evaluation in expressions. At first glance, these operators may seem similar because they can both be used to return a fallback value when the primary value is considered undesirable. However, their differences lie in the specific conditions under which they evaluate values, making each operator suited for different scenarios.
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Aug 2, 2024 | 
biorxiv.org | Sumit Kumar Singh |Kelvin Lee |Jayanth Venkatarama Reddy |Thomas Leibiger
AbstractChinese Hamster Ovary (CHO) cells were grown at different bioreactor pH conditions to detail how bioreactor pH affects cell metabolism and site-specific N-linked glycosylation of the produced broadly neutralizing anti-HIV IgG monoclonal antibody VRC01. The data show that pH affects cell growth, glucose/lactate metabolism, IgG production rates, nonessential amino acid metabolism and ammonia accumulation.
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Jul 3, 2024 | 
sumitkumarsingh.medium.com | Sumit Kumar Singh
Product prioritisation is not only one of the most challenging part of a PMs daily life, but also an essential part of the product manager's role. By leveraging proven frameworks like RICE, the Value vs. Effort Matrix, and Story Mapping, you can make data-driven decisions that align with your product's goals and your company's objectives. The key is to choose the framework(s) that provide the most clarity and alignment for your team, stakeholders, and customers.
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May 6, 2024 | 
sumitkumarsingh.medium.com | Sumit Kumar Singh
Guesstimates are critical components of consulting interviews, testing your ability to tackle complex problems with ease. U nderstanding Guesstimates: Guesstimates, often encountered in consulting case interviews, are rapid estimations used to assess a candidate's analytical thinking and problem-solving abilities. Despite their initial complexity, guesstimates are fundamentally straightforward calculations made within a brief timeframe, typically 10-15 minutes.
