Sushant Kumar

Jan 24, 2025 | biorxiv.org | Juan Du |Wei Lu |Sushant Kumar |Fei Jin

AbstractDetecting noxious heat is vital for survival, triggering pain responses that protect against harm. The TRPM3 channel is a key nociceptor for sensing noxious heat and a promising therapeutic target for pain treatment and neurological disorders such as epilepsy. Here, we functionally and structurally characterized TRPM3 in response to diverse stimuli: the synthetic superagonist CIM0216, the anticonvulsant antagonist primidone, and heat.

Dec 8, 2024 | medium.com | Sushant Kumar

Sushant Kumar·Follow5 min read·--I’ll admit it — when I first encountered wrapper classes in Java, I was confused. Why would I ever need a fancy Integer when I could just use int? It felt like adding unnecessary complexity to something that was already working just fine. But then reality hit. I wanted to store numbers in a list, handle nullable values from a database, and pass data to methods that only accepted objects. Suddenly, primitives alone weren’t cutting it.

Nov 23, 2024 | medium.com | Sushant Kumar

Sushant Kumar·Follow5 min read·--Maven Dependency GraphAs developers, we’ve all been there — watching Maven effortlessly resolve dependencies and build our projects, no matter how complex the dependency graph gets. It’s a feature so reliable that most of us don’t think twice about how it works. I was the same until one day, curiosity struck. How does Maven decide the right build order when faced with dozens of interconnected modules?

Nov 16, 2024 | medium.com | Sushant Kumar

Sushant Kumar·Follow6 min read·--December 2021 was a watershed moment for the software industry, especially for those of us working with Java. The infamous Log4j vulnerability, known as Log4Shell, exposed a hidden risk buried in one of the most widely used logging libraries for Java applications. It felt like a wake-up call — reminding every developer, team, and organization of the potential dangers lurking in our dependencies.

Nov 9, 2024 | medium.com | Sushant Kumar

Sushant Kumar·Follow10 min read·--Imagine if you could code in multiple languages within a single project, all on the same platform — no more switching runtimes or battling with integrations. This week, we’re diving into GraalVM, a tool that makes this dream a reality. With GraalVM, you can call Python from Java, use JavaScript alongside R, or mix in other languages without any of the usual barriers.