Tao Shen

Dec 22, 2024 | mdpi.com | Tao Shen

2. Related WorksIn this section, advanced lightweight transformers are briefly reviewed. The current binary operators are also discussed to illustrate the key bottlenecks in binarization of deep networks. 2.1. Lightweight TransformersQuantization can effectively reduce the model size and computational costs, replacing expensive floating-point operations with simple fixed-point operations.

Nov 25, 2024 | mdpi.com | Wei Shi |Tao Shen |Xiaoyang Cheng |Xiaocui Zhuang

1. IntroductionDandelion is a kind of nutritious wild vegetable, also named Taraxaci Herba by the 2020 edition of the Pharmacopoeia of the People’s Republic of China, as well as a general term used for various perennial herbaceous plants in the genus Taraxacum, family Asteraceae [1,2]. As a traditional Chinese medicine, dandelion is well known for its bitter and sweet taste, cold nature, and its ability to enter the liver and stomach meridians.

Nov 21, 2024 | nature.com | Tao Shen |Siqi Sun |Di Liu |Jiuming Wang |Jin Xiao |Sheng Wang | +2 more

AbstractAccurate prediction of RNA three-dimensional (3D) structures remains an unsolved challenge. Determining RNA 3D structures is crucial for understanding their functions and informing RNA-targeting drug development and synthetic biology design. The structural flexibility of RNA, which leads to the scarcity of experimentally determined data, complicates computational prediction efforts.

Oct 28, 2024 | pubs.rsc.org | Dong Li |Ling Zhang |Daixi Li |Tao Shen

Paired electrocatalysis enabled oxidative coupling of styrenes with alkyl radicals A paired electrocatalysis strategy for intermolecular oxidative cross-dehydrocoupling between styrenes and ethers or p-methylphenol derivatives using ketone as mild oxidant is described. This approach allows Csp3 carbon-centered radicals to be generated by anodic oxidation, cross-coupled reductive coupling of ketone on the cathode, providing valuable oxidative alkylation products.

Sep 9, 2024 | nature.com | Tao Shen

AbstractNon-small cell lung cancer (NSCLC) constitutes a significant portion of lung cancers and cytotoxic drugs (e.g. cisplatin) are currently the first-line treatment. However, NSCLC has developed resistance to this drug, which limits the therapeutic effect and thus affects prognosis. NSCLC sc-RNA-seq data were downloaded from the GEO database and Ku Leuven Laboratory for Functional Epigenetics, and bulk RNA-seq data were obtained from the TCGA database.