Sheng Wang

Jan 14, 2025 | biorxiv.org | Huaizhi Qu |Xiao Wang |Yuanyuan Zhang |Sheng Wang

AbstractCryogenic electron microscopy (cryo-EM) has become a widely used technique for determining the 3D structures of proteins. However, cryo-EM datasets often exhibit heterogeneity, with protein particle images from multiple conformations or compositional states. Here we propose CryoNeRF, a novel neural radiance fields (NeRF)-based cryo-EM reconstruction framework operating directly in Euclidean 3D space.

Jan 14, 2025 | mdpi.com | Sheng Wang |Changxu Song |Li Zhang |Fengjiao Hu

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Jan 7, 2025 | nature.com | Sheng Wang |Carsten Kuenne |Stefan Günther |Nina Wettschureck |Young-June Jin |Mohamad Wessam Alnouri

AbstractAtherosclerotic lesions develop preferentially in arterial regions exposed to disturbed blood flow, where endothelial cells acquire an inflammatory phenotype. How disturbed flow induces endothelial cell inflammation is incompletely understood. Here we show that histone H3.3 phosphorylation at serine 31 (H3.3S31) regulates disturbed-flow-induced endothelial inflammation by allowing rapid induction of FOS and FOSB, required for inflammatory gene expression.

Dec 31, 2024 | mdpi.com | Sheng Wang

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Dec 11, 2024 | pubs.acs.org | Feng Xiong |Quanli Ke |Mei Lu |Sheng Wang

1. IntroductionClick to copy section linkSection link copied!Ultrahigh-molecular-weight polyethylene (UHMWPE) is one of the most important materials in military equipment, security protection, and aerospace fields, but high-purity ethylene (C2H4, ≥99.95%) is required to produce UHMWPE.