Theodore Nelson

Jun 11, 2024 | nature.com | Eliah G. Overbey |JangKeun Kim |Braden T. Tierney |Jiwoon Park |Deena Najjar |Remi Klotz | +30 more

AbstractSpaceflight induces molecular, cellular, and physiological shifts in astronauts and poses myriad biomedical challenges to the human body, which are becoming increasingly relevant as more humans venture into space1-6. Yet, current frameworks for aerospace medicine are nascent and lag far behind advancements in precision medicine on Earth, underscoring the need for rapid development of space medicine databases, tools, and protocols.

Jun 11, 2024 | nature.com | Christopher Jones |Eliah G. Overbey |Cem Meydan |Braden T. Tierney |Jiwoon Park |Theodore Nelson | +14 more

AbstractHuman spaceflight has historically been managed by government agencies, such as in the NASA Twins Study1, but new commercial spaceflight opportunities have opened spaceflight to a broader population.

Jun 10, 2024 | nature.com | Kirill Grigorev |Theodore Nelson |Eliah G. Overbey |JangKeun Kim |Deena Najjar |Jean Thierry-Mieg | +1 more

AbstractThe advent of civilian spaceflight challenges scientists to precisely describe the effects of spaceflight on human physiology, particularly at the molecular and cellular level. Newer, nanopore-based sequencing technologies can quantitatively map changes in chemical structure and expression at single molecule resolution across entire isoforms.

Jan 20, 2024 | biorxiv.org | Theodore Nelson |Claire Walter |Julianna K. Rose |Gresia L. Cervantes-Navarro

AbstractTen years ago, it was predicted that the multi-omics revolution would also revolutionize space pharmacogenomics. Current barriers related to the findable, accessible, interoperable, and reproducible use of space-flown pharmaceutical data have contributed to a lack of progress beyond application of earth-based principles.