Thomas Metz

Jan 19, 2025 | nature.com | Lisa M. Bramer |Ernesto S. Nakayasu |Michael J MacCoss |Thomas Metz

AbstractThe deployment of liquid chromatography-mass spectrometry-based plasma proteomics experiments in a large cohort is sparse, leading to a lack of data available for benchmarking, method development or validation. Comprised of 6,426 plasma analyses, The Environmental Determinants of Diabetes in the Young (TEDDY) proteomics validation study constitutes one of the largest targeted proteomics experiments in the literature to date.

Aug 4, 2023 | pubs.rsc.org | Lucas Webber |Lindsey Anderson |Ines L. Paraiso |Thomas Metz

Affinity- and activity-based probes synthesized from structurally diverse hops-derived xanthohumol flavonoids reveal highly varied protein profiling in Escherichia coli† Xanthohumol, the principle prenylflavonoid found in hops (Humulus lupulus) and a reported anti-inflammatory agent, has great potential for pharmaceutical interventions related to inflammatory disorders in the gut.